THE BASIC PRINCIPLES OF PENTOBARBITAL SODIUM OVER THE COUNTER

pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of CYP3A4 inducers may well reduce sufentanil amounts and efficacy, quite possibly precipitating withdrawal syndrome in individuals who definitely have created physical dependence to sufentanil.